Two terrorists break into a reseach laboratory and are contaminated with a deadly virus. One escapes and boards a train which has the usual selection of stereotype characters. The train is isolated and sent towards an isolation camp in Poland, but over a bridge that is reputed to be unsafe. This is a typical disaster style film from the 1970's with a strong cast list and good performances from Sophia Loren and Richard Harris as the divorced couple having to work together on the train and Ava Gardner in a different outfit in each scene.